| Date | Location | Result | |
| 3/6/12 | LJVMC - Winston-Salem, NC | N.C. Central 60, U. of Maryland Eastern Shore 43 | Box score |
| 03/01/12 | Princess Anne, Md. (WP Hytche) | Savannah State 73, U. of Maryland Eastern Shore 54 | Box score |
| 02/27/12 | Princess Anne, Md. (WP Hytche Center) | Coppin State 64, U. of Maryland Eastern Shore 60 | Box score |
| 02/25/12 | Princess Anne, Md. (WP Hytche) | U. of Maryland Eastern Shore 58, MORGAN STATE 57 | Box score |
| 2/20/12 | Burr Gymnasium - Washington, DC | Howard 53, U. of Maryland Eastern Shore 51 | Box score |
| 2/15/12 | Hampton, Va. (HU Convocation Center) | Hampton 82, U. of Maryland Eastern Shore 62 | Box score |
| 2/13/12 | Baltimore, Md. (Physical Ed. Complex) | Coppin State 81, U. of Maryland Eastern Shore 78 | Box score |
| 2/11/12 | HILL FIELD HOUSE, BALTIMORE, Md. | U. of Maryland Eastern Shore 68, MORGAN STATE 56 | Box score |
| 02/06/12 | Princess Anne, Md. (WP Hytche Center) | Norfolk State 72, U. of Maryland Eastern Shore 60 | Box score |
| 02/04/12 | Princess Anne, Md. (WP Hytche Center) | U. of Maryland Eastern Shore 78, Howard 65 | Box score |
| 01/30/12 | Durham, N.C. - McDougald-McLendon Gym | N.C. Central 77, U. of Maryland Eastern Shore 46 | Box score |
| 1/28/12 | Greensboro, N.C. (Corbett Sports Ctr.) | North Carolina A&T 91, U. of Maryland Eastern Shore 66 | Box score |
| 01/23/12 | Princess Anne, Md. (WP Hytche Center) | Bethune-Cookman 67, U. of Maryland Eastern Shore 55 | Box score |
| 01/21/12 | Princess Anne, Md. (WP Hytche Center) | Florida A&M 68, U. of Maryland Eastern Shore 63 | Box score |
| 01/14/12 | Dover, Del. (Memorial Hall) | U. of Maryland Eastern Shore 63, Delaware State Univ. 60 | Box score |
| 01/07/12 | Norfolk, Va. (Echols Hall) | Norfolk State 78, U. of Maryland Eastern Shore 72 | Box score |
| 01/03/12 | Stabler Arena - Bethlehem, Pa. | Lehigh 82, U. of Maryland Eastern Shore 55 | Box score |
| 12/27/11 | Charlottesville, Va. (JPJA) | Virginia 69, U. of Maryland Eastern Shore 42 | Box score |
| 12/17/11 | USAFA, Colo. (Clune Arena) | Air Force 64, U. of Maryland Eastern Shore 60 | Box score |
| 12/10/11 | Princess Anne, Md. WP Hytche Ath. Center | U. of Maryland Eastern Shore 95, Mercy 69 | Box score |
| 12/03/11 | Princess Anne, Md., WP Hythce Ath Center | Delaware State Univ. 78, U. of Maryland Eastern Shore 68 | Box score |
| 11/30/11 | Princess Anne, Md. WP Hytche Ath. Center | U. of Maryland Eastern Shore 59, NAVY 46 | Box score |
| 11/27/11 | Laramie, Wyo. (Arena-Auditorium) | Portland State 79, U. of Maryland Eastern Shore 69 | Box score |
| 11/26/11 | Laramie, Wyo. (Arena-Auditorium) | Wyoming 73, U. of Maryland Eastern Shore 43 | Box score |
| 11/25/11 | Laramie, Wyo. (Arena-Auditorium) | Louisiana Tech 73, U. of Maryland Eastern Shore 54 | Box score |
| 11/22/11 | Manhattan, Kan. - Bramlage Coliseum | Kansas State 92, U. of Maryland Eastern Shore 50 | Box score |
| 11/20/11 | Tudor Fieldhouse - Houston, Texas | Rice 81, U. of Maryland Eastern Shore 49 | Box score |
| 11/18/11 | New Orleans, La. (Fogelman Arena) | Tulane 73, U. of Maryland Eastern Shore 52 | Box score |
| 11/14/11 | Princess Anne, Md. | U. of Maryland Eastern Shore 64, AMERICAN 62 | Box score |
| 11/11/11 | Charles E. Smith Center - Washington, DC | George Washington 64, U. of Maryland Eastern Shore 48 | Box score |