| Date | Location | Result | |
| 03/10/10 | LJVM Coliseum - Winston-Salem, NC | Hampton 65, Maryland Eastern Shore 41 | Box score |
| 03/09/10 | LJVM Coliseum - Winston-Salem, NC | Maryland Eastern Shore 52, Delaware State 45 | Box score |
| 03/04/10 | Dover,Del.-Memorial Hall | Maryland Eastern Shore 58, Delaware State 55 | Box score |
| 2/27/10 | Burr Gymnasium - Washington, DC | Howard 62, Maryland Eastern Shore 57 | Box score |
| 02/22/10 | W.P. Hytche Center (Princess Anne, Md.) | Maryland Eastern Shore 66, Morgan State 64 | Box score |
| 2/20/10 | William P. Hytche Athletic Center | Maryland Eastern Shore 76, Coppin State 56 | Box score |
| 02/17/10 | W.P. Hytche Center (Princess Anne, Md.) | Florida A&M 75, Maryland Eastern Shore 67 | Box score |
| 02/15/10 | Princess Anne, Md. (W.P. Hytche Center) | Bethune-Cookman 61, Maryland Eastern Shore 54 | Box score |
| 2/8/10 | Greensboro, NC (Corbett Sports Center) | North Carolina A&T 76, Maryland Eastern Shore 46 | Box score |
| 02/06/10 | Norfolk, Va. (Echols Hall) | Maryland Eastern Shore 76, Norfolk State 56 | Box score |
| 02/01/10 | Princess Anne, Md. (W.P. Hytche Center) | Hampton 64, Maryland Eastern Shore 48 | Box score |
| 01/30/10 | Princess Anne, Md. (W.P. Hytche Center) | Howard 55, Maryland Eastern Shore 51 | Box score |
| 01/27/10 | Princess Anne, Md. (W.P. Hytche Center) | Maryland Eastern Shore 64, North Carolina Central 43 | Box score |
| 01/25/10 | Baltimore, Md. (Hill Field House) | Morgan State 65, Maryland Eastern Shore 51 | Box score |
| 1/23/10 | Baltimore, Md. (Physical Educ. Complex) | Maryland Eastern Shore 55, Coppin State 53 | Box score |
| 1/18/10 | Moore Gymnasium, Daytona Beach, Fla. | Bethune-Cookman 56, Maryland Eastern Shore 55 | Box score |
| 1/16/10 | Tallahassee, Fla. (Al Lawson Center) | Maryland Eastern Shore 47, Florida A&M 43 | Box score |
| 01/11/10 | Princess Anne, Md. (W.P. Hytche Center) | Maryland Eastern Shore 65, Winston-Salem State 38 | Box score |
| 01/09/10 | Princess Anne, Md. (W.P. Hytche Center) | Maryland Eastern Shore 82, South Carolina State 69 | Box score |
| 01/07/10 | Durham, NC (McDougald-McLendon Gym) | North Carolina Central 69, Maryland Eastern Shore 60 | Box score |
| 01/04/10 | Bender Arena - Washington, D.C. | American 57, Maryland Eastern Shore 46 | Box score |
| 12/30/09 | GSU Sports Arena/Atlanta, Ga. | Georgia State 76, Maryland Eastern Shore 49 | Box score |
| 12/29/09 | GSU Sports Arena/Atlanta, Ga. | Maryland Eastern Shore 61, Miss. Valley State 49 | Box score |
| 12/07/09 | Princess Anne, Md. (W.P. Hytche Center) | Iona 53, Maryland Eastern Shore 50 | Box score |
| 12/05/09 | Princess Anne, Md. (W.P. Hytche Center) | Maryland Eastern Shore 74, Delaware State 61 | Box score |
| 11/24/09 | Brooklyn, N.Y. (Wellness Center) | Long Island 81, Maryland Eastern Shore 71 | Box score |
| 11/22/09 | Riverdale, N.Y.-Draddy Gymnasium | Manhattan 88, Maryland Eastern Shore 58 | Box score |
| 11/15/09 | Baltimore, Md. (RAC Arena) | UMBC 102, Maryland Eastern Shore 65 | Box score |